Prof.이기용
Prof.이기용
직위 또는 학위 : 부교수
Tel : 044-860-1623
E-mail : kylee11@korea.ac.kr
연구분야 : 생약학(Pharmacognosy)
이기용
부교수, 약학박사
약학대학 약학과
고려대학교 세종캠퍼스
세종특별자치시 세종로 2511, 30019, 대한민국
Phone : +82-44-860-1623
Fax : +82-44-860-1606
E-mail : kylee11@korea.ac.kr
학력사항
⦁ 1995년 3월 ~ 1999년 2월; 서울대학교 약학대학 (약학사, 약학전공)
⦁ 1999년 3월 ~ 2001년 2월; 서울대학교 약학대학원 (약학석사, 생약학전공)
⦁ 2001년 3월 ~ 2007년 2월; 서울대학교 약학대학원 (약학박사, 생약학전공)
주요경력
⦁ 2013년 2월 ~ 현재; 고려대학교 약학대학, 조교수, 부교수
⦁ 2013년 3월 ~ 현재; 고려대학교 의과대학 의학과, 겸임조교수, 겸임부교수
⦁ 2012년 3월 ~ 2013년 2월; 서울대학교 종합약학연구소, 선임연구원, 연구조교수
⦁ 2009년 9월 ~ 2011년 11월; 미시간주립대학교, Visiting Research Associate
⦁ 2007년 10월 ~ 2009년 8월; 서울대학교 BK21 응용생명약학사업단, 연수연구원
⦁ 2007년 3월 ~ 2009년 8월; ㈜엘컴사이언스, 생명과학연구소, 책임연구원
⦁ 2007년 3월 ~ 2007년 9월; 서울대학교 약학대학 종합약학연구소, 선임연구원
학회/대외활동
⦁ 2017년 1월 ~ 현재; 대한약학회 영문지편집간사
⦁ 2016년 2월 ~ 현재; 한국약학교육평가원, 약학대학 및 실무실습교육기관 평가위원
⦁ 2014년 8월 ~ 현재; 식품의약품안전처 중앙약사심의위원회전문가단, 전문가
⦁ 2017년 1월 ~ 2017년 12월; 한국생약학교수협의회, 재무이사
⦁ 2015년 1월 ~ 2016년 12월; 한국생약학회, 재무이사
⦁ 2014년 1월 ~ 2016년 12월; 식품의약품안전처 「천연물의약품 산업발전협의체」 기준∙규격분과, 위원
⦁ 2014년 1월 ~ 2015년 12월; 여성생명과학기술포럼, 운영위원
⦁ 1999년 3월 ~ 현재; 한국생약학회 학생회원, 정회원, 종신회원, 대의원
⦁ 1999년 10월 ~ 현재; 대한약학회 학생회원, 정회원
2015년 이후 국제학술지 연구실적
2018년
1. Buyun Kim, Ki Yong Lee*, Byoungduck Park*. Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-κB/ERK signaling pathway in Raw264.7 cells. Phytomedicine, In press, Available online 23 June 2018 (*co-corresponding author) 2. Hyo Hee Yang, Kyung-Eon Oh, Yang Hee Jo, Jong Hoon Ahn, Qing Liu, Ayman Turk, Jae Young Jang, Bang Yeon Hwang, Ki Yong Lee*, Mi Kyeong Lee*. Comparison of antibacterial activity and phenolic constituents of bark, lignum, leaves and fruit of Rhus verniciflua.PLoS One. 13(7): e0200257 (2018) (*co-corresponding author) 3. Sangmin Park, Hyeji Shin, Yeeun Park, Ilgyu Choi, Byoungduck Park*, Ki Yong Lee*. Characterization of inhibitory constituents of NO production from Catalpa ovata using LC-MS coupled with a cell-based assay. Bioorganic Chemistry 80 (2018) 57–63 (2018) (*co-corresponding author) 4. Jong Hoon Ahn, Yang Hee Jo, Seon Beom Kim, Ayman Turk, Kyung-Eon Oh, Bang Yeon Hwang, Ki Yong Lee*, Mi Kyeong Lee*. Identification of antioxidant constituents of the aerial part of Plantago asiatica using LC–MS/MS coupled DPPH assay. Phytochemistry Letters 26:20-24 (2018) (*co-corresponding author) 5. Hyeji Shin, Yeeun Park, Young Ho Jeon, Xi-Tao Yan, and Ki Yong Lee*. Identification of Polygonum orientale constituents using high-performance liquid chromatography high-resolution tandem mass spectrometry. Bioscience, Biotechnology, and Biochemistry 82(1):15-21 (2018) 6. Hyo Hee Yang, Kyung-Eon Oh,Yang Hee Jo, Jong Hoon Ahn, Qing Liu, Ayman Turk, Jae Young Jang, Bang Yeon Hwang, Ki Yong Lee*, Mi Kyeong Lee.* Characterization of tyrosinase inhibitory constituents from the aerial parts of Humulus japonicus using LC-MS/MS coupled online assay. Bioorganic & Medicinal Chemistry 26(2):509-515 (2018) (*co-corresponding author) 7. Hyeji Shin, Carl Angelo Medriano, Byoungduck Park, Youngja H Park, Ki Yong Lee*. Screening and identification of neuroprotective compounds from Scrophularia buergeriana using cell extraction coupled with LC–MS. Journal of Pharmaceutical and Biomedical Analysis 148, 355-360 (2018) 2017년
8. Jeong Hoon Pan, Yejin Lim, Jun Ho Kim, Wan Heo, Ki Yong Lee, Hye Ji Shin, Jae Kyeom Kim, Jin Hyup Lee, Young Jun Kim. Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation. PLoS One. 12(11):e0188381 (2017) 9. Seonghu Park, Yeeun Park, Sang-Hyun Son, Kiho Lee, Yong Woo Jung, Ki Yong Lee, Young Ho Jeon, Young joo Byun. Synthesis and biological evaluation of peptide-derived TSLP inhibitors. Bioorganic & Medicinal Chemistry Letters 27, 4710–4713 (2017) 10. Ameeq Ul Mushtaq, Jeong Soon Park, Sung-Hun Bae, Hye-Yeon Kim, Kwon Joo Yeo, Eunha Hwang, Ki Yong Lee, Jun-Goo Jee, Hae-Kap Cheong, Young Ho Jeon. Ligand-Mediated Folding of the OmpA Periplasmic Domain from Acinetobacter baumannii. Biophysical Journal 112(10), 2089-2098 (2017) 11. Buyun Kim, Ki Yong Lee*, Byoung duck Park*. Crocin Suppresses Constitutively Active STAT3 through Induction of Protein Tyrosine Phosphatase SHP-1. Journal of Cellular Biochemistry 118(10), 3290-3298 (2017) (*co-corresponding author) 12. Hong mok Kwon, Joo Yeon Han, Ki Yong Lee, Sang-Hyun Son, Young joo Byun. Recent advances of hepsin-targeted inhibitors. Current Medicinal Chemistry 24(21), 2294-2311 (2017) 13. Hyeji Shin, Yeeun Park, Ji Hoon Choi, Young Ho Jeon, Youngjoo Byun, Sang Hyun Sung*, Ki Yong Lee*. Structure elucidation of a new triterpene from Rhus trichocarpa roots. Magnetic Resonance in Chemistry 55(8), 763-766 (2017) (*co-corresponding author) 14. Seung-min Yeon, Ju Hyung Lee, Daewon Kang, Hyuna Bae, Ki Yong Lee, Seohoon Jin, Jung Ryul Kim, Yong Woo Jung, Tae Won Park. A cytokine study of pediatric Tourette’s disorder without obsessive compulsive disorder. Psychiatry Research 247, 90-96 (2017) 2016년
15. Yun Hee Jeong, You-Chang Oh, Won-Kyung Cho, Hyeji Shin, Ki Yong Lee*, Jin Yeul Ma*. Anti-inflammatory effects of Viola yedoensis and the application of cell extraction methods for investigating bioactive constituents in macrophages. BMC Complementary and Alternative Medicine 16(1), 180 (2016) (*co-corresponding author) 16. Kyung-Eon Oh, Hyeji Shin, Young Ho Jeon, Yang Hee Jo, Mi Kyeong Lee, Ken S. Lee, Byoungduck Park*, Ki Yong Lee*. Optimization of pancreatic lipase inhibitory and antioxidant activities of Ilex paraguariensis by using response surface methodology. Archives of Pharmacal Research 39(7), 946-952 (2016) (*co-corresponding author) 17. Jeong Hoon Pan#, Ki Yong Lee#, Eui Seop Lee, Jin Hyup Lee, Young Jun Kim. Prunus mume Sieb. et Zucc. fruit ameliorates alcoholic liver injury in mice by inhibiting apoptosis and inflammation through oxidative stress. Journal of Functional Foods 25, 135-148 (2016) (#Both authors contributed equally to this work) 18. Ki Yong Lee*, Ji Hoon Choi, Hyeon Woo Kim, Xi-Tao Yan, Hyeji Shin, Young Ho Jeon, Sang Hyun Sung*. New alkyl phloroglucinol derivatives from Rhus trichocarpa roots and their cytotoxic effects on human gastric adenocarcinoma AGS cells. Planta Medica 82(7), 645-649 (2016) (*co-corresponding author) 19. Ki Yong Lee, Eun Ju Jeong, Sang Hyun Sung, Young Choong Kim. Stemona alkaloids isolated from Stemona tuberosa roots and their inhibitory activity on lipopolysaccharide-induced nitric oxide production. Records of Natural Products 10(1), 109-112 (2016) 2015년
20. Ji Yeon Jeong, Yang Hee Jo, Seon Beom Kim, Qing Liu, Jin Woo Lee, Eun Jin Mo, Ki Yong Lee, Bang Yeon Hwang, Mi Kyeong Lee. Pancreatic lipase inhibitory constituents from Morus alba leaves and optimization for extraction conditions. Bioorganic & Medicinal Chemistry Letters 25(11), 2269-74 (2015) 21. Ji-Hyun Park, Ki Yong Lee, Byoungduck Park, Jaewoo Yoon. Suppression of Th2-chemokines by crocin via blocking of ERK-MAPK/NF-κB/STAT1 signaling pathways in TNF[alpha]/IFN[gamma]-stimulated human epidermal keratinocytes. Experimental Dermatology 24(8):634-636 (2015) 22. Ji-Hyun Park, Jaewoo Yoon, Ki Yong Lee*, Byoungduck Park*. Effects of geniposide on hepatocytes under going epithelial-mesenchyma l transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways. Biochimie 113, 26-34 (2015) (*co-corresponding author) 23. Eun Ju Jeong, Na-Hyun Kim, Jeong-Doo Heo, Ki Yong Lee, Jung-Rae Rho, Young Choong Kim, Sang Hyun Sung. Antifibrotic Compounds from Liriodendron tulipifera Attenuating HSC-T6 Proliferation and TNF-α Production in RAW264.7 Cells. Biological & Pharmaceutical Bulletin 38(2), 228-234 (2015) 주요연구분야
⦁ Neurodegenerative diseases 치료제 개발을 위한 활성 천연물 탐색, 발굴 및 구조 규명
⦁ 천연물 chemical profile 설정 및 phytoequivalence 확보를 위한 phytoanalysis
⦁ Quantitative pattern-activity relationship (QPAR)을 이용한 천연물의 화학적 특징과 활성의 상관관계 규명
⦁ 생약학 I
⦁ 생약학 II
⦁ 약학실습 V (생약학실험)
⦁ 천연물약품학
⦁ 의약품품질관리학
Current Members
이기용교수님 Lab Members 
신혜지 (Hyeji Shin)
석박통합과정
E-mail : hjshin90@korea.ac.kr
한유경 (Yoo Kyong Han)
박사과정
E-mail : yookyong05@korea.ac.kr
남미현 (Mi-hyun Nam)
석박통합과정
E-mail : skaaus@korea.ac.kr
오경언 (Kyung-Eon Oh)
석사과정
E-mail : ok1000sa@korea.ac.krGraduated Members
이기용교수님 Lab Members 
정윤희 (Yun Hee Jeong)
한국한의학연구원
E-mail : runxi0333@kiom.re.kr
박상민 (Sangmin Park)
한국콜마
E-mail : parkmin1@naver.com
박다원 (Dawon Park)
한국유나이티드제약
E-mail : pye7906@naver.com